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  • Title: Cytomegalovirus-associated superior mesenteric vein thrombosis treated with systemic and in-situ thrombolysis.
    Author: Van Moerkercke W, Pauwelyn K, Brugman E, Verhamme M.
    Journal: Eur J Gastroenterol Hepatol; 2009 May; 21(5):587-92. PubMed ID: 19373975.
    Abstract:
    A 56-year-old patient, first diagnosed with an acute cytomegalovirus infection, presented with progressive abdominal pain because of a superior mesenteric vein thrombosis for which he was treated with systemic thrombolysis and heparin in continuous infusion. As this therapy did not have the intended success after 5 days, an interventional radiological procedure was performed with local thrombolysis in the superior mesenteric artery resulting in recanalisation of the vein. Oral anticoagulation was initiated and continued for a period of 6 months. Mesenteric venous thrombosis is a relatively uncommon cause of mesenteric ischemia that can be associated with severe morbidity and significant mortality. With noninvasive techniques, it is possible to establish a diagnosis in the majority of the cases. The importance of an early diagnosis and therapy - not only with anticoagulation, but also thrombolysis in selected cases - is shown with this case and review of the literature.
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