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  • Title: Population structure and distribution of virulence-related genes of Bacteroides fragilis isolates from Korea and Japan.
    Author: Ko KS, Kuwahara T, Lee K, Kook YH.
    Journal: Diagn Microbiol Infect Dis; 2009 Jul; 64(3):340-3. PubMed ID: 19376671.
    Abstract:
    Sequences for rpoB, gyrB, pdiA, and ompA were determined from 63 Bacteroides fragilis isolates, which were from Korea and Japan and include 4 reference strains. All 4 gene sequences supported clear separation of the cfi(+) group from the cfi(-) group. Combined sequences of the 60 division I isolates (cfi(-)) produced 45 different clones. Apparent discordance of gene trees, index of association, maximum likelihood test, and homoplasy ratio all supported a high frequency of recombination. There was no association between the presence of virulence-related genes and phylogenetic clustering in any gene tree.
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