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  • Title: Estimation of fiber orientation probability density functions in high angular resolution diffusion imaging.
    Author: Tristán-Vega A, Westin CF, Aja-Fernández S.
    Journal: Neuroimage; 2009 Aug 15; 47(2):638-50. PubMed ID: 19393321.
    Abstract:
    An estimator of the Orientation Probability Density Function (OPDF) of fiber tracts in the white matter of the brain from High Angular Resolution Diffusion data is presented. Unlike Q-Balls, which use the Funk-Radon transform to estimate the radial projection of the 3D Probability Density Function, the Jacobian of the spherical coordinates is included in the Funk-Radon approximation to the radial integral. Thus, true angular marginalizations are computed, which allows a strict probabilistic interpretation. Extensive experiments with both synthetic and real data show the better capability of our method to characterize complex micro-architectures compared to other related approaches (Q-Balls and Diffusion Orientation Transform), especially for low values of the diffusion weighting parameter.
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