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Title: Steroidal saponins from the whole plants of Agave utahensis and their cytotoxic activity. Author: Yokosuka A, Mimaki Y. Journal: Phytochemistry; 2009 Apr; 70(6):807-15. PubMed ID: 19394982. Abstract: Phytochemical investigation of the whole plants of Agave utahensis Engelm. (Agavaceae) has resulted in the isolation of 15 steroidal saponins (1-15), including five spirostanol saponins (1-5) and three furostanol saponins (11-13). Structures of compounds 1-5 and 11-13 were determined by spectroscopic analysis and the results of hydrolytic cleavage. The isolated compounds were evaluated for their cytotoxic activity against HL-60 human promyelocytic leukemia cells.[Abstract] [Full Text] [Related] [New Search]