These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Effects of Liuweidihuang Decoction on cell proliferation and melanin synthesis of cultured human melanocytes in vitro].
    Author: Deng Y, Liu Z, Xiao Y, Liu YJ.
    Journal: Nan Fang Yi Ke Da Xue Xue Bao; 2009 Apr; 29(4):701-3. PubMed ID: 19403399.
    Abstract:
    OBJECTIVE: To investigate the effects of Liuweidihuang Decoction on the proliferation and melanin synthesis of cultured human melanocytes in vitro. METHODS: MTT assay was used to assess the proliferation of cultured human melanocytes after treatment with Liuweidihuang Decoction, and NaOH assay was employed to determine melanin synthesis. RESULTS: Liuweidihuang Decoction at the concentration of 5%-15% did not affect the proliferation of the melanocytes (P>0.05), and the decoction at 20%-30% significantly inhibited the cell proliferation, especially at the optimal concentration of 30% (P<0.01). The decoction promoted melanin synthesis in the melanocytes at the concentration of 10%-15% with the optimal concentration of 15% (P<0.01) but failed to produce such an effect at 20%-30%. CONCLUSION: Liuweidihuang Decoction exert a two-way regulation on the proliferation and melanin synthesis of cultured human melanocytes in vitro.
    [Abstract] [Full Text] [Related] [New Search]