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  • Title: IL-21: a new player in the control of isotype switch in Peyer's patches.
    Author: Pistoia V, Cocco C.
    Journal: J Leukoc Biol; 2009 May; 85(5):739-43. PubMed ID: 19406834.
    Abstract:
    Peyer's patches (PP) are lymphoid follicles of the small intestine containing predominantly IgA(+) B cells. In this JLB issue, IL-21 is reported to dampen TGF-beta1-induced IgG2b but not IgA production by mouse B cells, possibly explaining why IgA(+) B cells predominate in PP.
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