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  • Title: Comparison of two prognostic scores for patients with parotid carcinoma.
    Author: Takahama A, Sanabria A, Benevides GM, de Almeida OP, Kowalski LP.
    Journal: Head Neck; 2009 Sep; 31(9):1188-95. PubMed ID: 19408288.
    Abstract:
    BACKGROUND: Salivary glands present a wide diversity in histopathologic types and biologic behaviors, thus complicating the search for prognostic factors. METHODS: We compared 2 prognostic scores that were previously published for patients with parotid carcinoma in a retrospective series of 175 patients treated in a single institution. RESULTS: Cox multivariate analysis indicated clinical skin invasion, facial nerve function, and perineural growth as the most significant recurrent disease-related prognostic factors. According to the Vander Poorten score, 148 patients were divided into 4 groups, with the 5-year disease-free survival of 76%, 81%, 69%, and 35%, respectively. In the Carrillo's score, the patients were divided into 3 groups: low-risk, intermediate-risk, and high-risk, with the 5-year disease-free survival of 84%, 73%, and 34%, respectively. CONCLUSION: Carrillo's score showed more distinct survival curves, and determination of groups with a more favorable prognosis was difficult for both scores. Therefore, both scores were not totally reproducible for our group of patients.
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