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  • Title: [Study on bioavailability of Fe-riched wheat varieties using an in vitro digestion/Caco-2 cell model].
    Author: Lei J, Huang C, Zhang Y, Zhang M.
    Journal: Wei Sheng Yan Jiu; 2009 Mar; 38(2):166-9. PubMed ID: 19408658.
    Abstract:
    OBJECTIVE: To select the most promising Fe-riched wheat varieties by studying Fe bioavailability from several wheat variety flours so as to provide scientific evidence for further human trials and nutrition target in wheat breeding. METHODS: The Fe bioavailability among 10 Fe-riched wheat flours was assessed using an in vitro/Caco-2 cell culture model. Caco-2 cell ferritin formation was measured as an indicator of Fe utilized by human Caco-2 exposing to tested flour digests. RESULTS: Significant differences were detected in Fe bioavailability among 10 flour varieties, Zhongyou 9507 (from Anyang) and Jingdong 8 with 78% flour yield had the highest Fe bioavailability. CONCLUSION: The two most promising varieties, Zhongyou 9507 (from Anyang) and Jingdong 8 will be further evaluated in human trials to determine their efficacy.
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