These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Pediatric multicentric glioma occurring after cranial irradiation.
    Author: Tsutsumi S, Yasumoto Y, Ito M.
    Journal: J Clin Neurosci; 2009 Aug; 16(8):1086-8. PubMed ID: 19409792.
    Abstract:
    An 8-year-old girl with no family history of neoplasia underwent biopsy and chemoradiation therapy for a suprasellar mixed germ cell tumor, which resulted in complete remission. A surveillance MRI taken 37 months after irradiation detected a non-enhancing mass in the genu of the corpus callosum. MRI taken 42 months after irradiation revealed significant growth of the mass and a new enhancing lesion in the temporal lobe, which showed rapid growth over 3 weeks. Subtotal resection and biopsy were performed on the lesions in the temporal lobe and the corpus callosum, respectively. Histological examination revealed that the temporal tumor was a glioblastoma multiforme and the frontal lesion was a diffuse astrocytoma. These tumors had newly developed within the irradiated field, but were separated in both location and time. Radiation-induced gliomas may develop within a shorter time interval than previously considered.
    [Abstract] [Full Text] [Related] [New Search]