These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Stiffening effect of cholesterol on disordered lipid phases: a combined neutron spin echo + dynamic light scattering analysis of the bending elasticity of large unilamellar vesicles.
    Author: Arriaga LR, López-Montero I, Monroy F, Orts-Gil G, Farago B, Hellweg T.
    Journal: Biophys J; 2009 May 06; 96(9):3629-37. PubMed ID: 19413968.
    Abstract:
    In this study, the center-of-mass diffusion and shape fluctuations of large unilamellar 1-palmitoyl-2-oleyl-sn-glycero-phosphatidylcholine vesicles prepared by extrusion are studied by means of neutron spin echo in combination with dynamic light scattering. The intermediate scattering functions were measured for several different values of the momentum transfer, q, and for different cholesterol contents in the membrane. The combined analysis of neutron spin echo and dynamic light scattering data allows calculation of the bending elastic constant, kappa, of the vesicle bilayer. A stiffening effect monitored as an increase of kappa with increasing cholesterol molar ratio is demonstrated by these measurements.
    [Abstract] [Full Text] [Related] [New Search]