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  • Title: An efficient one-pot copper-catalyzed approach to isoquinolin-1(2H)-one derivatives.
    Author: Wang F, Liu H, Fu H, Jiang Y, Zhao Y.
    Journal: Org Lett; 2009 Jun 04; 11(11):2469-72. PubMed ID: 19422263.
    Abstract:
    A simple and efficient copper-catalyzed method for synthesis of 3,4-disubstituted isoquinolin-1(2H)-one derivatives via cascade reactions of substituted 2-halobenzamides with beta-keto esters under mild conditions has been developed, and the method has economical and practical advantages.
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