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  • Title: Pituitary adenoma with craniopharyngioma component.
    Author: Gokden M, Mrak RE.
    Journal: Hum Pathol; 2009 Aug; 40(8):1189-93. PubMed ID: 19427020.
    Abstract:
    Neoplasms consisting of pituitary adenoma and craniopharyngioma components are rare and are being increasingly recognized. Their histogenesis is not clear. Most represent collision tumors; others are difficult to assess. Here, we describe a pituitary adenoma with an intermingled craniopharyngioma component, without forming 2 distinct mass lesions or histologic delineation. Areas that suggest a transition between the 2 components were also present. It was clinically a nonfunctioning adenoma, which was also negative for pituitary hormones by immunohistochemistry. Its histogenesis and implications are discussed with a review of the literature.
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