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  • Title: Thymolipoma: clues to pathogenesis revealed by cytogenetics.
    Author: Hudacko R, Aviv H, Langenfeld J, Fyfe B.
    Journal: Ann Diagn Pathol; 2009 Jun; 13(3):185-8. PubMed ID: 19433298.
    Abstract:
    The pathogenesis of thymolipoma is controversial and unclear despite numerous reports. A case report of thymolipoma with cytogenetic analysis is herein presented. The lesion demonstrated a translocation involving the HMGA2 gene on chromosome 12q15, which is seen in two thirds of solitary lipomas. This finding supports the theory that this case of thymolipoma is a neoplasm of thymic fat.
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