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  • Title: [Study on chemical constituents and antimicrobial activity of the essential oil from Acanthopanax brachypus].
    Author: Hu HS, Hu HB, Zheng XD.
    Journal: Zhong Yao Cai; 2009 Jan; 32(1):67-70. PubMed ID: 19445125.
    Abstract:
    OBJECTIVE: The chemical constituents and antimicrobial activity of the essential oil from Acanthopanax brachypus were studied. METHODS: The essential oil was extracted from the stem of A. brachypus by steam distillation, and its antimicrobial activity was tested in vitro. The chemical constituents were separated and identified by GC-MS, and the relative contents of each constituent was determined by area normalization. RESULTS: The essential oil showed some certain antibacterial activities against the tested strains escherichia coli, bacillus subtilis, staphylococcus aureus, pseudomonas aeruginosa and candida albicans except aspergillus niger. Forty-seven constituents were separated and identified, accounting for 91.37% of the total oil. The main constituent were Heptanoic acid (7.05%), Vanillin (6.09%), trans-Linalool oxide (6.07%), 1-methyl-2-(-methylethyl)-Benaene (5.83%), alpha-Phellandrene (5.14%), n-Hexadecanoic acid (5.15%) and beta-Myrcene (5.07%). CONCLUSION: The essential oil of A. brachypus contained varied active constituent, has a certain antimicrobial activity, this result will provide some scientific references for the pharmacological further research of A. brachypus.
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