These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [AOTF-near infrared spectroscopy for determining tanshinone II A in returning extraction process of Salvia miltiorrhiza].
    Author: Wu WH, Wang N, Cai SS, Wei H.
    Journal: Zhong Yao Cai; 2009 Jan; 32(1):118-21. PubMed ID: 19445136.
    Abstract:
    OBJECTIVE: To explore a method on-line determining the contents of tanshinone II A in returning extraction process of Salvia miltiorrhiza by AOTF-Near infrared spectroscopy. METHODS: Firstly, the sample was collected in the extraction process of Salvia miltiorrhiza. Then HPLC was used as a reference method to determine the contents of tanshinone II A in the sample. Multivariate calibration models based on PLS1 algorithm were developed to correlate the spectra and the corresponding values determined by the reference methods. RESULTS: RMSECV of the models for tanshinone II A was 0.0092. The correlation coefficients of the calibration models was 0.9918. External validation with external validation samples proved that the relative deviation was 5.74%. CONCLUSIONS: AOTF-NIRS can be used in the determination of tanshinone II A in returning extraction process of Salvia miltiorrhiza. The method is rapid, accurate and non-destructive, and can be applied for process analysis and quality control of Chinese medicine manufacturing process.
    [Abstract] [Full Text] [Related] [New Search]