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  • Title: [Polypharmacy and psychotropic drugs as risk factors for falls in long-term care setting for elderly patients in Lombardy].
    Author: Baranzini F, Poloni N, Diurni M, Ceccon F, Colombo D, Colli C, Ferrari G, Callegari C.
    Journal: Recenti Prog Med; 2009 Jan; 100(1):9-16. PubMed ID: 19445275.
    Abstract:
    Aim of the study was to investigate polypharmacy and psychotropic drugs as risk factors for falls in a Long-term Care Setting for elderly patients. In a cross-sectional study we investigated the characteristics of 414 subjects: 207 fallen patients 44 (21.3%) male e 163 (78.7%) female mean age 84.16 +/- 8.3 y.o. First generation neuroleptics (OR 1.739 CI 95% 1.047-2.889), benzodiazepines (OR 2.357 CI 95% 1.5-3.702) and mood stabilizers (OR 1.889 CI 95% 1.091-3.270) were associated to falls when adjusted for age, sex and comorbidities. Polypharmacotherapy (> or = 4 drugs) was a risk factor for falls when associated to a risk medication in the daily regimen only (OR 2.157 CI 95% 1.447-3.217). What raised has to be taken into account in the prescriptive activities in a Long term Care Setting for elderly patients.
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