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  • Title: [Changes in the patients' mental status in the tolerability of antituberculous drugs].
    Author: Mordyk AV, Briukhanova NS, Kazakov AV.
    Journal: Probl Tuberk Bolezn Legk; 2009; (3):38-42. PubMed ID: 19455986.
    Abstract:
    The impact of disease and treatment on the mental status of patients with infiltrative pulmonary tuberculosis was studied. The study included 39 patients, chemotherapy in whom was complicated by the development of adverse reactions and 33 patients who had no adverse reactions. In new cases of tuberculosis, anxiety and personality disorders before chemotherapy were ascertained to be a response to first diagnosed tuberculosis and forced long-term in the inpatient setting. The development of adverse reactions caused by antituberculous agents during therapy was accompanied by impairments in psychological adaptation processes, the preservation and worsening of anxiety and personality disorders, which determines it necessary to include additional drug and psychotherapeutic correction methods into a package of therapeutic measures in tuberculosis.
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