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  • Title: Primary cutaneous blastoid mantle cell lymphoma-case report.
    Author: Estrozi B, Sanches JA, Varela PC, Bacchi CE.
    Journal: Am J Dermatopathol; 2009 Jun; 31(4):398-400. PubMed ID: 19461249.
    Abstract:
    Mantle cell lymphoma (MCL) commonly involves extranodal sites, usually as a manifestation of disseminated disease. In rare cases, MCLs may arise as a primary tumor in the skin. Blastoid mantle cell lymphoma (BV-MCL) is a rare variant and has a more aggressive clinical course. The phenotype of BV-MCL is characterized as CD20+, CD5+, cyclin D1+, CD23-, and CD10-. Interphase fluorescence in situ hybridization shows a characteristic t(11;14) fusion pattern. We report a case of a BV-MCL arising in skin as primary cutaneous MCL with the characteristic immunophenotype and translocation.
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