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Title: [Flow cytometric basophils activation test as a method of allergy diagnosis]. Author: Potapińska O, Demkow U, Wasik M. Journal: Pneumonol Alergol Pol; 2009; 77(2):152-8. PubMed ID: 19462349. Abstract: For several years the incidences of allergic diseases and anaphylactic reactions have been increasing dramatically. Classical method of allergy diagnosis - skin prick test in some situations can provoke life-threatening reactions. Detection of allergen-induced basophil activation by flow cytometry has been shown to be a useful tool for allergy diagnosis in those patients. CD 63 and CD203c have recently been demonstrated as a specific activation markers of basophils that are rapidly up-regulated after allergen challenge in sensitized patients. Although flow-cytometry methods are quite sophisticated and expensive, it could be a good alternative in patients at risk of severe anaphylactic reactions or with contradictory test results.[Abstract] [Full Text] [Related] [New Search]