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  • Title: Repenins A-D, four new antioxidative coumarinolignoids from Duranta repens Linn.
    Author: Ahmad N, Zeb F, Ahmad I, Wang F.
    Journal: Bioorg Med Chem Lett; 2009 Jul 01; 19(13):3521-4. PubMed ID: 19464173.
    Abstract:
    Phytochemical investigations on the CHCl(3)-soluble fraction of the whole plant of Duranta repens Linn. led to the isolation of four new coumarinolignoids, Repenins A-D (1-4), along with the known coumarinolignoids, cleomiscosin A (5) and durantin A (6). Their structures were determined by modern spectroscopic analysis including 1D and 2D NMR techniques and chemical studies. The compounds (1-6) showed potent antioxidative scavenging activity against DPPH radicals, with IC(50) values in the range 0.420-0.625mM. Repenin B (2) displayed the strongest scavenging potential with IC(50) values of (0.420mM).
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