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  • Title: Methicillin-resistant Staphylococcus aureus (MRSA) osteomyelitis of the mandible.
    Author: Tuzuner-Oncul AM, Ungor C, Dede U, Kisnisci RS.
    Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 Jun; 107(6):e1-4. PubMed ID: 19464635.
    Abstract:
    Methicillin-resistant Staphylococcus aureus (MRSA) is a type of Staphylococcus that is resistant to certain antibiotics, such as methicillin, oxacillin, penicillin, and amoxicillin. This nosocomial pathogen has become a great threat in hospitals globally. Up to 40% of the normal population carries S. aureus in the anterior nares, and this rate is often higher in hospitalized patients and their attendants. This case report presents a patient with serious MRSA osteomyelitis of the mandible demonstrating purulent discharge. The patient failed to recover despite prolonged postoperative treatment and the administration of several antibiotics. There was a resulting nonunion along with chronic MRSA infection. The treatment protocol involved a multimodal approach with parenteral clindamycin infusion, local rifampicin irrigation, and intermaxillary fixation of the jaws.
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