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  • Title: Finger length ratio (2D:4D) in left- and right-handed males.
    Author: Stoyanov Z, Marinov M, Pashalieva I.
    Journal: Int J Neurosci; 2009; 119(7):1006-13. PubMed ID: 19466635.
    Abstract:
    The finger length ratio (2D:4D) is a biomarker for the prenatal levels of testosterone. The prenatal effects of testosterone on the development of brain hemispheres are considered as a key factor in the etiology of left-handedness. We tested whether 2D:4D correlates with the type of handedness in males (18 right-handers and 18 left-handers). Right hand 2D:4D, left hand 2D:4D, average 2D:4D, and the difference between right and left 2D:4D (D(r-l)) were compared. The value of D(r-l) in left-handers was significantly lower than D(r-l) in right-handers. This result can be interpreted as proof that left-handers were subjected to higher levels of testosterone in utero.
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