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  • Title: Developmentally regulated cyclic AMP-dependent protein kinases in Dictyostelium discoideum.
    Author: Sampson J.
    Journal: Cell; 1977 May; 11(1):173-80. PubMed ID: 194703.
    Abstract:
    Two apparently distinct species of cyclic AMP-dependent protein kinase appear during the first 1-2 hr of development in Dictyostelium discoideum; no such activity can be detected in vegetative cell extracts. These two kinases are similar in properties to the type I and II cyclic AMP-dependent protein kinases found in a number of mammalian tissues. Their time of appearance supports the idea that one or both mediate the effects of cyclic AMP on gene expression early in Dictyostelium development.
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