These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
Pubmed for Handhelds
PUBMED FOR HANDHELDS
Search MEDLINE/PubMed
Title: [Cortisone-induced osteoporosis: from physiopathogenesis to treatment]. Author: Peretz A. Journal: Rev Med Brux; 1991 Oct; 12(8):321-8. PubMed ID: 1947526. Abstract: Glucocorticoids are useful as therapeutic agents in a wide variety of clinical disorders for their antiinflammatory, immunosuppressive and cytolytic properties. When administered in supraphysiological doses they cause an array of undesired side-effects that greatly limit their clinical utility. Among them, the development of osteoporosis is critical. It is a multifactorial process with important actions occurring in bone and other sites. As a consequence, an uncoupling of bone turnover is observed with a decrease in bone formation and an increase in bone resorption. The efficacy of preventive and therapeutic interventions are limited but an area of new perspectives are currently under investigation.[Abstract] [Full Text] [Related] [New Search]