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Title: A graphene platform for sensing biomolecules. Author: Lu CH, Yang HH, Zhu CL, Chen X, Chen GN. Journal: Angew Chem Int Ed Engl; 2009; 48(26):4785-7. PubMed ID: 19475600. Abstract: Sensitive platform: The use of graphene oxide (GO) as a platform for the sensitive and selective detection of DNA and proteins is presented. The interaction of GO and dye-labeled single-stranded DNA leads to quenching of the dye fluorescence. Conversely, the presence of a target DNA or protein leads to the binding of the dye-labeled DNA and target, releasing the DNA from GO, thereby restoring the dye fluorescence (see picture).[Abstract] [Full Text] [Related] [New Search]