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  • Title: Quadrivalent meningococcal conjugate vaccines.
    Author: Pace D, Pollard AJ, Messonier NE.
    Journal: Vaccine; 2009 Jun 24; 27 Suppl 2():B30-41. PubMed ID: 19477560.
    Abstract:
    Neisseria meningitidis is an important cause of bacterial meningitis and septicaemia with most disease caused by meningococci bearing serogroups A, B, C, Y and W-135 polysaccharides. Monovalent serogroup C conjugate vaccines have become established in the immunisation programmes in many countries and the first quadrivalent meningococcal vaccine, containing the polysaccharides from 4 of the serogroups A, C, Y and W-135 meningococci conjugated to a protein carrier was licensed in the US in 2005. This vaccine and others in development offer the potential to broaden population protection against meningococcal disease.
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