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  • Title: The second wind phenomenon in very young McArdle's patients.
    Author: Pérez M, Ruiz JR, Fernández Del Valle M, Nogales-Gadea G, Andreu AL, Arenas J, Lucía A.
    Journal: Neuromuscul Disord; 2009 Jun; 19(6):403-5. PubMed ID: 19477644.
    Abstract:
    We investigated the phenomenon of second wind in four patients with McArdle's disease: a brother and sister (aged 4 and 12 years respectively) and two unrelated patients, a boy of 14 and a 17-year-old girl. We also studied the siblings' healthy 6-year-old sister. Each patient performed a 15-min exercise test at a constant workload and a subsequent graded exercise test until exhaustion. Overall the healthy girl and the youngest McArdle's patient, the 4-year-old boy, did not show a second wind phenomenon. Further, the peak cardio-respiratory capacity of the young McArdle's boy was normal for his age (32.3 mL 02/kg/min) and he did not report any function limitations during physical education classes.
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