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  • Title: [Zygomycoses: clinical aspects and pathology in 10 patients].
    Author: Donhuijsen K, Grothey A, Völker B, Dermoumi H.
    Journal: Schweiz Med Wochenschr; 1991 Oct 12; 121(41):1493-8. PubMed ID: 1947946.
    Abstract:
    Deep fungal infections caused by zygomycetes (so-called mucormycoses) are rare. Whereas in the past rhinocerebral mycosis dominated, today a wide range of clinical manifestations must be expected, especially pulmonary infections and invasion of vessel walls with systemic infarction. On the basis of 10 cases of Mucoraceae mycosis and a review of the literature, the predisposing conditions, clinical symptoms and pathologic-anatomic findings are described. Our observations include 7 patients with leukemia and 2 adults and one newborn without malignant neoplasia. Except for the patient with rhinocerebral mycosis, the diagnosis was not established during the patients' lifetime. 3 patients received systemic antimycotic therapy. Our observations suggest that infarctions of internal organs in immunocompromised patients should direct suspicion towards angio-related mycoses, not only of aspergillosis, but also of zygomycosis.
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