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  • Title: Antimitotic activity of lobaric acid and a new benzofuran, sakisacaulon A from Stereocaulon sasakii.
    Author: Morita H, Tsuchiya T, Kishibe K, Noya S, Shiro M, Hirasawa Y.
    Journal: Bioorg Med Chem Lett; 2009 Jul 01; 19(13):3679-81. PubMed ID: 19481447.
    Abstract:
    Lobaric acid (1) has been isolated from lichen, Stereocaulon sasakii together with a new benzofuran, sakisacaulon A (2). Lobaric acid (1) inhibited the polymerization of tubulin. Structure-activity relationship of lobaric acid and its derivatives on inhibitory activity of tubulin polymerization was discussed.
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