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  • Title: Synthesis and antimicrobial activity of 4-hydroxy-4-(pyridyl)alk-3-en-2-ones.
    Author: Riahi A, Wurster M, Lalk M, Lindequist U, Langer P.
    Journal: Bioorg Med Chem; 2009 Jul 01; 17(13):4323-6. PubMed ID: 19481948.
    Abstract:
    4-Hydroxy-4-(pyridyl)alk-3-en-2-ones were prepared by base-mediated condensation of ketones with pyridinecarboxylates. Several derivatives show weak antimicrobial activity against Gram-positive and Gram-negative bacteria.
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