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  • Title: Scalarane-based sesterterpenoid RCE-protease inhibitors isolated from the Indonesian marine sponge Carteriospongia foliascens.
    Author: Williams DE, Hollander I, Feldberg L, Frommer E, Mallon R, Tahir A, van Soest R, Andersen RJ.
    Journal: J Nat Prod; 2009 Jun; 72(6):1106-9. PubMed ID: 19485329.
    Abstract:
    Two new 20,24-bishomo-25-norscalaranes, compounds 1 and 2, and two new and two known 20,24-bishomoscalaranes, compounds 3-6, have been isolated from the Indonesian marine sponge Carteriospongia foliascens. The structures of 1-6 were determined by spectroscopic analysis. Compounds 1 and 3-6 inhibit RCE-protease activity.
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