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  • Title: Simple cyclohexanediamine-derived primary amine thiourea catalyzed highly enantioselective conjugate addition of nitroalkanes to enones.
    Author: Mei K, Jin M, Zhang S, Li P, Liu W, Chen X, Xue F, Duan W, Wang W.
    Journal: Org Lett; 2009 Jul 02; 11(13):2864-7. PubMed ID: 19485350.
    Abstract:
    A highly enantioselective conjugate addition of nitroalkanes to enones has been developed. The process is efficiently catalyzed by a simple chiral cyclohexanediamine-derived primary amine thiourea with a broad substrate scope.
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