These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Biokinetics and biotransformation of DDTs in the marine green mussels Perna viridis.
    Author: Kwong RW, Yu PK, Lam PK, Wang WX.
    Journal: Aquat Toxicol; 2009 Jul 26; 93(4):196-204. PubMed ID: 19487035.
    Abstract:
    The biokinetics of p,p'-dichlorodiphenyltrichloroethane (DDT) and its metabolites, p,p'-dichlorodiphenydichloroethylene (DDE) and p,p'-dichlorodiphenyldichloroethane (DDD), in the green-lipped mussel Perna viridis were characterized in this study. We exposed the mussels to DDT in aqueous or dietary sources and then compared and evaluated the absorption, accumulation, distribution and elimination of DDT and its metabolites (DDD and DDE) in the mussels. In addition, a dynamic model was employed to quantify the depuration kinetics of each DDT compound in various organs of the mussels. The potential biotransformation pathway in the mussels after dietary exposure to DDT was also analyzed. Differing accumulation and elimination patterns of each DDT compound (DDT, DDD and DDE) in various organs were observed. Most of the DDT was confined to the hepatopancreas following either aqueous or dietary exposure, although the biological fate and biokinetics of DDT were differed significantly between routes of exposure. In addition, the elimination of dietary DDT was markedly slower than that following aqueous uptake. The biotransformation of DDT to DDE was rare in the mussels, suggesting that any DDE in the mussels came primarily from the ambient environment instead of through biotransformation process. Nevertheless, DDE may be retained in the mussels because of its exceptionally low elimination rate. In contrast, DDT was biotransformed to DDD in the mussels following dietary uptake, and this biotransformation may facilitate DDT elimination from the mussels.
    [Abstract] [Full Text] [Related] [New Search]