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  • Title: Plant lectins: potential antineoplastic drugs from bench to clinic.
    Author: Liu B, Bian HJ, Bao JK.
    Journal: Cancer Lett; 2010 Jan 01; 287(1):1-12. PubMed ID: 19487073.
    Abstract:
    Plant lectins, carbohydrate-binding proteins distributed widely in a variety of plant species, have drawn a rising attention for cancer biologists due to their remarkable anti-tumour properties. In this review, we present a brief outline of the up-to-date advances of plant lectins in elucidating their complex anti-cancer mechanisms implicated in apoptosis and autophagy. In addition, we further discuss the pre-clinical and clinical studies of plant lectins for their potential therapeutic applications. In conclusion, these inspiring findings would open a new perspective for plant lectins as potential antineoplastic drugs from bench to clinic.
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