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  • Title: [Escherichia coli reactions to the action of the cationic proteins of blood leukocytes].
    Author: Zhdan-Pushkina SM, Rybakova LP.
    Journal: Zh Mikrobiol Epidemiol Immunobiol; 1991 Jul; (7):5-8. PubMed ID: 1950265.
    Abstract:
    The antibacterial effect of cation proteins (CP) of swine leukocytes with respect to Escherichia coli strain 17 has been demonstrated in vitro. The composition and properties of these CP have been studied; as a result, a comparatively high content of basic and dicarbonic amino acids and the presence of protease activity have been established. The release of the components of the metabolic fund by E. coli under the influence of CP of swine leukocytes is indicative of changes in the permeability of microbial membranes and, probably, of the deficiency of energy resources. The addition of heparin to CP of swine leukocytes levels their antibacterial effect with respect to E. coli.
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