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  • Title: [Efficiency of retrosternal lymphotropic chemotherapy in the treatment of new cases of destructive pulmonary tuberculosis].
    Author: Kibrik BS, Zakharov AV.
    Journal: Probl Tuberk Bolezn Legk; 2009; (4):23-7. PubMed ID: 19514450.
    Abstract:
    The efficiency of treatment was evaluated in 2 groups of new tuberculosis cases discharging drug-resistant Mycobacterium tuberculosis. The authors' method of retrosternal lymphotropic administration of drugs was used in the complex of treatment in a study group of 96 patients; a control group (n = 93) received only combined chemotherapy. The treatment method showed a high efficiency in the treatment of new cases of destructive pulmonary tuberculosis, including acutely progressive forms and caseous pneumonia. Bacterial discharge cessation and decay cavity closure were increased by 26.9% and 27.2%, respectively. The abacillation rate increment was 32.9% for acutely progressive processes and 41.2% for caseous pneumonia. The authors show the efficiency of the method in treating bronchial or laryngeal tuberculosis and the expediency of applying the retrosternal procedure during preoperative preparation.
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