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  • Title: Bayesian statistical reconstruction for low-dose X-ray computed tomography using an adaptive-weighting nonlocal prior.
    Author: Chen Y, Gao D, Nie C, Luo L, Chen W, Yin X, Lin Y.
    Journal: Comput Med Imaging Graph; 2009 Oct; 33(7):495-500. PubMed ID: 19515533.
    Abstract:
    How to reduce the radiation dose delivered to the patients has always been a important concern since the introduction of computed tomography (CT). Though clinically desired, low-dose CT images can be severely degraded by the excessive quantum noise under extremely low X-ray dose circumstances. Bayesian statistical reconstructions outperform the traditional filtered back-projection (FBP) reconstructions by accurately expressing the system models of physical effects and the statistical character of the measurement data. This work aims to improve the image quality of low-dose CT images using a novel AW nonlocal (adaptive-weighting nonlocal) prior statistical reconstruction approach. Compared to traditional local priors, the proposed prior can adaptively and selectively exploit the global image information. It imposes an effective resolution-preserving and noise-removing regularization for reconstructions. Experimentation validates that the reconstructions using the proposed prior have excellent performance for X-ray CT with low-dose scans.
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