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  • Title: Efficient three-component one-pot synthesis of fully substituted pyridin-2(1H)-ones via tandem Knoevenagel condensation-ring-opening of cyclopropane-intramolecular cyclization.
    Author: Liang F, Cheng X, Liu J, Liu Q.
    Journal: Chem Commun (Camb); 2009 Jun 28; (24):3636-8. PubMed ID: 19521633.
    Abstract:
    An efficient synthesis of fully substituted pyridin-2(1H)-ones was developed via three-component one-pot reactions of readily available 1-acetyl-1-carbamoyl cyclopropanes, malononitrile and cyclic secondary amines.
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