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  • Title: [Review of 32 gastro-intestinal stromal tumours with CD117 antigen].
    Author: Lahmar-Boufaroua A, Ben Slama S, Bouraoui S, Gharbi L, Goutallier C, Manai S, Gharbi W, Mzabi-Regaya S.
    Journal: Tunis Med; 2009 Feb; 87(2):133-6. PubMed ID: 19522447.
    Abstract:
    AIM: The aim of this study is to review clinical data, histological and immunohistochemical findings and prognosis of stromal gastrointestinal tumors. METHODS: A retrospective Study of 32 cases of stromal gastrointestinal tumors diagnosed in the Department of Pathology of Mongi Slim Hospital of Tunis from 1991 to 2004. RESULTS: The average age of the patients was of 54.4 years, equal for sex. Tumors were essentially gastric (50%) and of the small intestine (37.5%). All the patients had surgical treatment. Gastro-intestinal Stromal Tumors or GIST represent the most frequent stromal tumor with 56.2% of cases. CONCLUSION: After immunohistochimestry study, using CD117 antigen, this revision allows better management of GIST. Glivec is the standard treatment of advanced GIST.
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