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  • Title: [Pharmacological hypertension therapy].
    Author: Pedersen OL, Christensen KL, Bang LE, Ibsen H, Schultz-Larsen P.
    Journal: Ugeskr Laeger; 2009 Jun 08; 171(24):2022-5. PubMed ID: 19523367.
    Abstract:
    Drug therapy in uncomplicated hypertension can be initiated with either ACE-inhibitors, angiotensin II receptor antagonists, calcium channel blockers or thiazides. In younger patients, the first three classes are preferable. Beta-blockers are first-line drugs for hypertension in patients with cardiac comorbidity. Initial combination therapy is indicated in high-risk patients where blood pressure reduction of > 20/10 mmHg is desired. Resistant hypertension generally calls for an increment in diuretic dosage and/or addition of a potassium-sparing diuretic.
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