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  • Title: Comparative assessment of Helicobacter pylori colonization in children tonsillar tissues.
    Author: Jabbari Moghaddam Y, Rafeey M, Radfar R.
    Journal: Int J Pediatr Otorhinolaryngol; 2009 Sep; 73(9):1199-201. PubMed ID: 19523691.
    Abstract:
    OBJECTIVE: The objective was to survey the results of RUT (rapid urease test) in children tonsillar tissues. METHODS: In a prospective clinical study 285 children (4-14 years) tonsillar tissue tested with RUT (rapid urease test) and histopathologic biopsy and simultaneously serum IgG Helicobacter pylori level was measured for all patients. RESULTS: One hundred and thirteen patients (39.6%) were positive to H. pylori in histopathologic examination. Forty patients (14%) had positive RUT and 15 patients had positive serum IgG anti-H. pylori level. In 40 patients the results in both histopathology and RUT were positive (P=0.000) although in 172 patients the results in both histopatologhic and RUT were negative (P=0.000). CONCLUSIONS: This study showed that H. pylori was present in tonsillar tissue and RUT is not sensitive enough for diagnosis of H. pylori in tonsillar tissue. Indicating that H. pylori has a possible role in reservoir of H. pylori in children.
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