These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Label-free detection of specific DNA sequence-telomere using unmodified gold nanoparticles as colorimetric probes.
    Author: Qi Y, Li L, Li B.
    Journal: Spectrochim Acta A Mol Biomol Spectrosc; 2009 Sep 15; 74(1):127-31. PubMed ID: 19523870.
    Abstract:
    A simple and sensitive label-free colorimetric detection of telomere DNA has been developed. It was based on the color change of gold nanoparticles (AuNPs) due to DNA hybridization. UV-vis spectra and transmission electron microscopy (TEM) were used to investigate the change of AuNPs. Under the optimized conditions, the linear range for determination of telomere DNA was 5.7 x 10(-13) to 4.5 x 10(-6)mol/L. The detection limit (3 sigma) of this method has decreased to pico-molar level.
    [Abstract] [Full Text] [Related] [New Search]