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  • Title: Bioactive constituents from the stems of Dalbergia parviflora.
    Author: Songsiang U, Wanich S, Pitchuanchom S, Netsopa S, Uanporn K, Yenjai C.
    Journal: Fitoterapia; 2009 Oct; 80(7):427-31. PubMed ID: 19524648.
    Abstract:
    From the stems of Dalbergia parviflora, three known flavonoids, six known isoflavonoids, a new isoflavone, dalparvone (2) and a new cinnamyl derivative, dalparvinene (6) were isolated and characterized. Isoflavan 3 exhibited strong cytotoxicity against KB and NCI-H187 cell lines with IC(50) values of 0.53 and 2.04 microg/ml, respectively. Compound 6 demonstrated strong cytotoxicity against NCI-H187 with an IC(50) value of 1.46 microg/ml. Compounds 4 and 6 possessed moderate cytotoxicity against KB cells with IC(50) values of 6.78 and 9.89 microg/ml, respectively. In addition, 2 exhibited moderate antiplasmodial activity with an IC(50) value of 8.19 microg/ml.
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