These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Effects of electroacupuncture of different acupoints groups on blood pressure and heart rate variability in rats].
    Author: Gao YH, Chen SP, Wang JY, Xu QL, Liu JL.
    Journal: Zhen Ci Yan Jiu; 2009 Feb; 34(1):21-6. PubMed ID: 19526803.
    Abstract:
    OBJECTIVE: To observe the effect of electroacupuncture (EA) of different acupoint groups on mean arterial pressure (MAP) and heart rate variability (HRV) in hypotension rats. METHODS: A total of 70 Wistar female rats were randomized into model, "Neiguan" (PC 6)-"Daling" (PC 7), "Waiguan" (SJ 4)-"Yangchi" (SJ 5), "Tianshu" (ST 25)-"Wailing" (ST 26), "Dachangshu" (BL 25)-"Qihaishu" (BL 24), "Baihui" (GV 20)-"Qianshencong" (EX-HN), and"Guangming" (GB 37)-"Xuanzhong" (GB 39) groups, with 10 cases in each. Hypotension model was established by bleeding (2.5-3 ml) through carotid artery. Immediately after bleeding, EA (2/15 Hz, 1 mA, 30 min) was applied to the above-mentioned acupoints of the 6 EA groups. MAP and ECG were recorded, then HRV was analyzed by using software Chart 5.2.1. RESULTS: MAP declined significantly after bleeding. Compared with model group, MAP values of PC6-PC7 and GB37-GB39 groups increased significantly 15 min and 30 min after bleeding, and those of ST25-ST26 and GV20-EX-HN groups also increased apparently 30 min after bleeding (P<0.05). No marked effects were observed in EA of SJ4-SJ5 and BL25-BL24 groups (P>0.05). The effect of PC6-PC7 and GB37-GB39 groups was significantly superior to that of SJ4-SJ5, BL25-BL24 and GV20-EX-HN groups in elevating MAP 30 min after bleeding (P<0.05). Compared with model group, heart rate (HR) of PC6-PC7 group was increased significantly 15 min and 30 min after bleeding (P<0.05). After bleeding, low frequency (LF), LF/high frequency (HF) and very low frequency (VLF) increased apparently. Compared with model group, LF, LF/HF and VLF of PC6-PC7 and GB37-GB39 groups decreased significantly 30 min after bleeding (P<0.05), suggesting a better balancing effect of EA of PC6-PC7 and GB37-GB39 on the activities of sympathetic and vagus nerves. CONCLUSION: EA of different acupoint groups has its own relative specificity in regulating MAP and HR in the rat, and PC6-PC7 EA and GB37-GB39 EA have a better efficacy, which is closely associated with their effects in balancing activities of the autonomic nerve system.
    [Abstract] [Full Text] [Related] [New Search]