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  • Title: Recurrent malignant peripheral nerve sheath tumour in a patient with neurofibromatosis Type 1: a case report.
    Author: Dimou J, Jithoo R, Pitcher M, White G.
    Journal: J Clin Neurosci; 2009 Sep; 16(9):1221-3. PubMed ID: 19539475.
    Abstract:
    Malignant peripheral nerve sheath tumour (MPNST) is a rare, albeit well-described, complication of neurofibromatosis. We report a 58-year-old patient with known neurofibromatosis Type 1 (NF-1) who presented with an aggressive recurrent malignant peripheral nerve sheath tumour and spinal cord compression 5 weeks after undergoing tumour excision with thoracic (T)6-7 laminectomy. The case and literature review are instructive to those following NF-1 patients with regards to screening for, and management of, malignant conversion of plexiform neurofibroma.
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