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  • Title: Persistent superior oblique paresis as a manifestation of familial periodic cerebellar ataxia.
    Author: Bain PG, Larkin GB, Calver DM, O'Brien MD.
    Journal: Br J Ophthalmol; 1991 Oct; 75(10):619-21. PubMed ID: 1954213.
    Abstract:
    A brother and sister complained of persistent diplopia due to superior oblique palsies. The cause of their symptoms became apparent when they were diagnosed as having familial periodic cerebellar ataxia (FPCA), a rare autosomal dominant condition. Oral acetazolamide (250 mg twice daily) not only prevented all the periodic symptoms but also relieved their diplopia, which had been present between attacks.
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