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  • Title: Principles of neural ensemble physiology underlying the operation of brain-machine interfaces.
    Author: Nicolelis MA, Lebedev MA.
    Journal: Nat Rev Neurosci; 2009 Jul; 10(7):530-40. PubMed ID: 19543222.
    Abstract:
    Research on brain-machine interfaces has been ongoing for at least a decade. During this period, simultaneous recordings of the extracellular electrical activity of hundreds of individual neurons have been used for direct, real-time control of various artificial devices. Brain-machine interfaces have also added greatly to our knowledge of the fundamental physiological principles governing the operation of large neural ensembles. Further understanding of these principles is likely to have a key role in the future development of neuroprosthetics for restoring mobility in severely paralysed patients.
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