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  • Title: In vivo hypoglycemic effects of phenolics from the root bark of Morus alba.
    Author: Zhang M, Chen M, Zhang HQ, Sun S, Xia B, Wu FH.
    Journal: Fitoterapia; 2009 Dec; 80(8):475-7. PubMed ID: 19545615.
    Abstract:
    Moracin M (1), Steppogenin-4'-O-beta-D-glucosiade (2), Mullberroside A (3) were isolated from the root bark of Morus alba L. and identified by spectral evidence. Compounds 1, 2 and 3 were studied in hypoglycemic effects on alloxan-diabetic mice. The results showed that compounds 1, 2 and 3 all produced hypoglycemic effects. The compound 2 in a dose of 50 mg/kg exerted significant effect (p<0.05), 2 and 3 in a dose of 100 mg/kg exerted obviously effect (p<0.01). Meantime, the compound 1 in a dose of 100 mg/kg can make the fasting blood glucose level have decreasing tendency.
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