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  • Title: Resection of a giant malignant mediastinal peripheral nerve sheath tumour under cardiopulmonary bypass.
    Author: Su JW, Chua YL, Ong BH, Lim CH.
    Journal: Singapore Med J; 2009 Jun; 50(6):e199-200. PubMed ID: 19551295.
    Abstract:
    Malignant peripheral nerve sheath tumour (MPNST) is a rare occurrence in the mediastinum. It is biologically aggressive and is generally resistant to chemoradiation therapy. The mainstay of treatment is complete surgical resection. We report a large MPNST which invaded into the adjacent aortic wall in a 50-year-old man. Extensive resection, which included aortic reconstruction under cardiopulmonary bypass and deep hypothermic arrest, was necessary for a good long-term outcome.
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