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  • Title: A new cytotoxic casbane diterpene from Euphorbia pekinensis.
    Author: Liang QL, Dai CC, Jiang JH, Tang YP, Duan JA.
    Journal: Fitoterapia; 2009 Dec; 80(8):514-6. PubMed ID: 19560525.
    Abstract:
    A new cytotoxic casbane diterpene, named pekinenal, was isolated from the roots of Euphorbia pekinensis. Its structure was elucidated as 5alpha-hydroxy-1betaH,2alphaH-casba-3Z,7E,11E-triene-18-al by a combination of 1D- and 2D-NMR techniques and confirmed by X-ray crystallography. Pekinenal showed cytotoxic activity against all four human cancer cell lines tested.
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